Games like Mark of Cain
Games like Mark of Cain include Warhammer 40,000: Boltgun, Gunfire Reborn, Borderlands 2, BioShock Infinite, and CULTIC. We matched them by the tags players give Mark of Cain on Steam (Boomer Shooter, First-Person, Shooter, Action Roguelike, and Action): closest matches first, and among equally close ones the better-known games.

Warhammer 40,000: Boltgun
Shared: Boomer Shooter · Shooter · First-Person

Gunfire Reborn
Shared: FPS · Roguelite · Action

Borderlands 2
Shared: Shooter · Action · First-Person

BioShock Infinite
Shared: First-Person · Shooter · Action

CULTIC
Shared: Boomer Shooter · Shooter · First-Person

MULLET MADJACK
Shared: Boomer Shooter · FPS · Action

Roboquest
Shared: Action Roguelike · Shooter · FPS

DOOM
Shared: Shooter · Action · First-Person

POSTAL: Brain Damaged
Shared: Boomer Shooter · Shooter · Action

Serious Sam: Siberian Mayhem
Shared: Boomer Shooter · Shooter · First-Person

Call of Duty®
Shared: Shooter · First-Person · FPS

Bloodshed
Shared: Boomer Shooter · Action Roguelike · Action

Counter-Strike
Shared: Action · Shooter · First-Person

Nightmare Reaper
Shared: Boomer Shooter · Shooter · FPS

DUSK
Shared: Boomer Shooter · Shooter · FPS

SharpShooter3D
Shared: Boomer Shooter · First-Person · Shooter

Black Mesa
Shared: First-Person · Action · FPS

Anger Foot
Shared: Boomer Shooter · Shooter · FPS

Deadzone: Rogue
Shared: First-Person · FPS · Shooter

Crab Champions
Shared: Action Roguelike · Looter Shooter · Arcade

VLADiK BRUTAL
Shared: First-Person · Shooter · Action

Aimlabs
Shared: Shooter · First-Person · FPS

Forgive Me Father
Shared: Boomer Shooter · Shooter · Action

HROT
Shared: Boomer Shooter · Shooter · First-Person