Games like Lost Vessel
Games like Lost Vessel include Melvor Idle, IdleOn - The Incremental MMO, Path of Exile, Idle Champions of the Forgotten Realms, and Dragon Cliff. We matched them by the tags players give Lost Vessel on Steam (RPG, Indie, Idler, Sci-fi, and Automation): closest matches first, and among equally close ones the better-known games.

Melvor Idle
Shared: RPG · Idler · Indie

IdleOn - The Incremental MMO
Shared: Idler · RPG · Indie

Path of Exile
Shared: Loot · RPG · Indie

Idle Champions of the Forgotten Realms
Shared: Idler · Indie · RPG

Dragon Cliff
Shared: RPG · Idler · Loot

Bloobs Adventure Idle
Shared: RPG · Indie · Casual

Legends of Dragaea: Idle Dungeons
Shared: Idler · RPG · Automation

Diablo® IV
Shared: RPG · Loot · Online Co-Op

Warframe
Shared: RPG · Free to Play · Sci-fi

Albion Online
Shared: RPG · Crafting · Loot

Cookie Clicker
Shared: Idler · Indie · Casual

Factorio
Shared: Automation · Resource Management · Crafting

Palworld
Shared: Indie · Crafting · Online Co-Op

Shop Titans
Shared: Idler · Crafting · RPG

Stardew Valley
Shared: RPG · Indie · Crafting

Warhammer 40,000: Inquisitor - Martyr
Shared: RPG · Loot · Indie

Potion Craft: Alchemist Simulator
Shared: Indie · Crafting · RPG

Fortune Mill
Shared: Idler · Automation · Casual

Path of Idle: Old Gods Rising
Shared: RPG · Idler · Indie

Lootun
Shared: RPG · Loot · Automation

ARC Raiders
Shared: Sci-fi · PvE · Online Co-Op

Idle Pins
Shared: Idler · RPG · Loot

Palia
Shared: Crafting · RPG · Indie

挂姬恶魔 IDLE DEVILS
Shared: RPG · Indie · Loot