Games like Last Ember
Games like Last Ember include Vampire Survivors, Skul: The Hero Slayer, Hades, BlazBlue Entropy Effect, and The Binding of Isaac: Rebirth. We matched them by the tags players give Last Ember on Steam (Action, Action Roguelike, 2D, Automation, and Combat): closest matches first, and among equally close ones the better-known games.

Vampire Survivors
Shared: Action Roguelike · 2D · Indie

Skul: The Hero Slayer
Shared: Action · Action Roguelike · Indie

Hades
Shared: Action Roguelike · Action · Indie

BlazBlue Entropy Effect
Shared: Action Roguelike · Action · 2D

The Binding of Isaac: Rebirth
Shared: Action Roguelike · Indie · 2D

Rogue Legacy
Shared: Action Roguelike · Action · 2D

Have a Nice Death
Shared: Action Roguelike · 2D · Action

Megabonk
Shared: Action Roguelike · Action · Indie

The Binding of Isaac
Shared: Action Roguelike · Action · Indie

Dungreed
Shared: Action Roguelike · Action · 2D

Melvor Idle
Shared: 2D · Singleplayer · Indie

Timberman
Shared: Action · 2D · Casual

Risk of Rain (2013)
Shared: Action Roguelike · Action · Indie

Boneraiser Minions
Shared: Action Roguelike · 2D · Indie

Windowkill
Shared: Action · Action Roguelike · 2D

20 Minutes Till Dawn
Shared: Action Roguelike · Combat · Singleplayer

One Finger Death Punch
Shared: Action · Indie · 2D

Death Must Die
Shared: Action Roguelike · Action · 2D

Desktop Survivors 98
Shared: Action Roguelike · Action · 2D

Sephiria
Shared: Action Roguelike · Action · Combat

UnderMine
Shared: Action Roguelike · Action · Indie

A Dance of Fire and Ice
Shared: 2D · Singleplayer · Indie

Dead Cells
Shared: Action Roguelike · 2D · Action

Octogeddon
Shared: Action · Action Roguelike · Indie