Games like Labyrinth of the Witch
Games like Labyrinth of the Witch include Vampire Survivors, Hades II, Digimon Story Time Stranger, One Way Heroics, and Stoneshard. We matched them by the tags players give Labyrinth of the Witch on Steam (Roguelike, Mystery Dungeon, Pixel Graphics, RPG, and Female Protagonist): closest matches first, and among equally close ones the better-known games.

Vampire Survivors
Shared: Pixel Graphics · Roguelike · Roguelite

Hades II
Shared: Roguelike · Roguelite · Female Protagonist

Digimon Story Time Stranger
Shared: RPG · JRPG · Creature Collector

One Way Heroics
Shared: Mystery Dungeon · Roguelike · Roguelite

Stoneshard
Shared: Roguelike · RPG · Pixel Graphics

Sephiria
Shared: Roguelike · Pixel Graphics · Roguelite

Elin
Shared: Roguelike · RPG · Pixel Graphics

Hyperdimension Neptunia Re;Birth1
Shared: Female Protagonist · RPG · JRPG

Touhou Genso Wanderer -Reloaded-
Shared: Roguelike · RPG · Mystery Dungeon

The Binding of Isaac: Rebirth
Shared: Roguelike · Pixel Graphics · Singleplayer

Moonlighter
Shared: Pixel Graphics · Roguelike · Roguelite

Touhou Mystia's Izakaya
Shared: Pixel Graphics · RPG · Casual

Shiren the Wanderer: The Tower of Fortune and the Dice of Fate
Shared: Roguelike · Mystery Dungeon · RPG

Crypt of the NecroDancer
Shared: Roguelike · Pixel Graphics · Female Protagonist

Balatro
Shared: Roguelike · Pixel Graphics · Singleplayer

Peglin
Shared: Roguelike · Pixel Graphics · Roguelite

Dungreed
Shared: Roguelike · Pixel Graphics · Roguelite

Children of Morta
Shared: Roguelike · Pixel Graphics · RPG

Touhou Endless Dream
Shared: Roguelike · Roguelite · Cute

Azur Lane Crosswave
Shared: RPG · Female Protagonist · Cute

The Shimmering Horizon and Cursed Blacksmith
Shared: Mystery Dungeon · Roguelike · JRPG

Halls of Torment
Shared: Pixel Graphics · Roguelike · Roguelite

Star Renegades
Shared: Roguelike · Pixel Graphics · Roguelite

Tales of Berseria™
Shared: RPG · Female Protagonist · JRPG