Games like Isolation Simulator
Games like Isolation Simulator include Poppy Playtime, Outlast, Five Nights at Freddy's, Garten of Banban, and The Cabin Factory. We matched them by the tags players give Isolation Simulator on Steam (Simulation, Walking Simulator, Survival Horror, Immersive Sim, and Psychedelic): closest matches first, and among equally close ones the better-known games.

Poppy Playtime
Shared: Survival Horror · First-Person · Horror

Outlast
Shared: Survival Horror · First-Person · Horror

Five Nights at Freddy's
Shared: Survival Horror · Horror · First-Person

Garten of Banban
Shared: First-Person · Horror · Survival Horror

The Cabin Factory
Shared: Walking Simulator · Immersive Sim · Simulation

Layers of Fear (2016)
Shared: Walking Simulator · First-Person · Horror

Visage
Shared: Survival Horror · First-Person · Dark

Slender: The Arrival
Shared: Survival Horror · First-Person · Horror

Outlast 2
Shared: Survival Horror · First-Person · Horror

SOMA
Shared: Survival Horror · Horror · Dark

From The Darkness
Shared: Walking Simulator · First-Person · Dark

Garten of Banban 2
Shared: First-Person · Horror · Survival Horror

Five Nights at Freddy's: Sister Location
Shared: Survival Horror · First-Person · Horror

Who's at the door?
Shared: Simulation · Walking Simulator · Immersive Sim

What Remains of Edith Finch
Shared: Walking Simulator · First-Person · Mystery

Amnesia: A Machine For Pigs
Shared: Walking Simulator · First-Person · Horror

Five Nights at Freddy's 2
Shared: Survival Horror · Horror · First-Person

The Exit 8
Shared: Walking Simulator · Immersive Sim · First-Person

Five Nights at Freddy's 3
Shared: Survival Horror · First-Person · Horror

Bendy and the Ink Machine
Shared: First-Person · Survival Horror · Horror

Kiosk
Shared: Immersive Sim · First-Person · Simulation

Buckshot Roulette
Shared: Dark · First-Person · Horror

Five Nights at Freddy's 4
Shared: Survival Horror · First-Person · Horror

Choo-Choo Charles
Shared: Survival Horror · First-Person · Horror

