Games like Human Defense [RTS]
Games like Human Defense [RTS] include Creeper World 4, Ultimate Epic Battle Simulator 2, Total War: WARHAMMER III, Age of History 3, and Plague Inc: Evolved. We matched them by the tags players give Human Defense [RTS] on Steam (Casual, Strategy, Simulation, RTS, and Tower Defense): closest matches first, and among equally close ones the better-known games.

Creeper World 4
Shared: Tower Defense · RTS · Strategy

Ultimate Epic Battle Simulator 2
Shared: Simulation · Strategy · RTS

Total War: WARHAMMER III
Shared: Strategy · RTS · Grand Strategy

Age of History 3
Shared: Strategy · RTS · Grand Strategy

Plague Inc: Evolved
Shared: Strategy · Simulation · Casual

Hearts of Iron IV
Shared: Strategy · Grand Strategy · Simulation

Plants vs. Zombies GOTY Edition
Shared: Strategy · Casual · Tower Defense

Total War: WARHAMMER
Shared: Strategy · Simulation · Grand Strategy

Total War: WARHAMMER II
Shared: Strategy · RTS · Grand Strategy

Wargame: Red Dragon
Shared: Strategy · RTS · Wargame

Total War: THREE KINGDOMS
Shared: Strategy · RTS · Grand Strategy

Creeper World IXE
Shared: RTS · Tower Defense · Real Time Tactics

Game Dev Tycoon
Shared: Simulation · Strategy · Casual

Ultimate General: Civil War
Shared: Strategy · RTS · Real Time Tactics

911 Operator
Shared: Strategy · Simulation · Casual

Nodebuster
Shared: Casual · Strategy · Simulation

WARNO
Shared: Strategy · RTS · Wargame

Total War: ROME II - Emperor Edition
Shared: Strategy · Grand Strategy · RTS

Bloons TD 6
Shared: Strategy · Tower Defense · Casual

Crusader Kings III
Shared: Strategy · Simulation · Grand Strategy

Kingdom Heroes 8
Shared: RTS · Strategy · Real Time Tactics

Men of War: Assault Squad 2
Shared: Strategy · RTS · Simulation

Europa Universalis IV
Shared: Strategy · Simulation · Grand Strategy

Mini Motorways
Shared: Strategy · Casual · Simulation