Games like 四方行
Games like 四方行 include Potion Craft: Alchemist Simulator, Supermarket Simulator, The Guild 3, Shop Titans, and Stardew Valley. We matched them by the tags players give 四方行 on Steam (Simulation, Trading, Strategy RPG, Economy, and RPG): closest matches first, and among equally close ones the better-known games.

Potion Craft: Alchemist Simulator
Shared: Simulation · Crafting · Resource Management

Supermarket Simulator
Shared: Simulation · Economy · Trading

The Guild 3
Shared: Simulation · Economy · Life Sim

Shop Titans
Shared: Crafting · Trading · Economy

Stardew Valley
Shared: Simulation · RPG · Life Sim

The Guild II Renaissance
Shared: Simulation · Economy · Trading

Crusader Kings III
Shared: Simulation · RPG · Medieval

Kenshi
Shared: Strategy RPG · RPG · Simulation

Probably Stolen - Cyberpunk Shopkeeper Sim
Shared: Simulation · Trading · Shop Keeper

Megastore Simulator
Shared: Simulation · Economy · Life Sim

Cities: Skylines
Shared: Simulation · Economy · Resource Management

Retro Rewind - Video Store Simulator
Shared: Simulation · Shop Keeper · Resource Management

Europa Universalis V
Shared: Simulation · Trading · Economy

Roadside Research
Shared: Simulation · Shop Keeper · Resource Management

TCG Card Shop Simulator
Shared: Simulation · Economy · Trading

Foundation
Shared: Simulation · Resource Management · Medieval

Mall Simulator
Shared: Simulation · Economy · Trading

SAELIG
Shared: Simulation · RPG · Trading

The Guild II
Shared: Simulation · Trading · RPG

My Time at Portia
Shared: RPG · Simulation · Life Sim

Travellers Rest
Shared: Life Sim · RPG · Crafting

BidKing
Shared: Simulation · Life Sim · Strategy

Graveyard Keeper
Shared: Simulation · RPG · Crafting

Farthest Frontier
Shared: Resource Management · Economy · Medieval