Games like Express No. 6
Games like Express No. 6 include Layers of Fear (2016), The Stanley Parable, Quarantine Zone: The Last Check, Firewatch, and Superliminal. We matched them by the tags players give Express No. 6 on Steam (First-Person, Psychedelic, Realistic, Choices Matter, and Walking Simulator): closest matches first, and among equally close ones the better-known games.

Layers of Fear (2016)
Shared: First-Person · Walking Simulator · Psychedelic

The Stanley Parable
Shared: First-Person · Walking Simulator · Indie

Quarantine Zone: The Last Check
Shared: First-Person · Choices Matter · Realistic

Firewatch
Shared: First-Person · Walking Simulator · Atmospheric

Superliminal
Shared: First-Person · Puzzle · Psychedelic

What Remains of Edith Finch
Shared: First-Person · Walking Simulator · Atmospheric

POOLS
Shared: Realistic · Walking Simulator · First-Person

The Witness
Shared: First-Person · Puzzle · Singleplayer

Garten of Banban
Shared: First-Person · Singleplayer · 3D

Detroit: Become Human
Shared: Choices Matter · Cinematic · Singleplayer

The Cabin Factory
Shared: Choices Matter · Walking Simulator · First-Person

Riven
Shared: First-Person · Puzzle · Singleplayer

Kingdom Come: Deliverance II
Shared: First-Person · Realistic · Singleplayer

Summer of '58
Shared: First-Person · Walking Simulator · Realistic

No, I'm not a Human
Shared: Choices Matter · First-Person · Singleplayer

Platform 8
Shared: Walking Simulator · First-Person · Puzzle

Antichamber
Shared: First-Person · Puzzle · Singleplayer

The Looker
Shared: First-Person · Puzzle · Walking Simulator

MiSide
Shared: First-Person · 3D · Singleplayer

Kingdom Come: Deliverance
Shared: Realistic · First-Person · Singleplayer

ROUTINE
Shared: Singleplayer · Cinematic · First-Person

Poppy Playtime
Shared: First-Person · Singleplayer · Puzzle

The Beginner's Guide
Shared: First-Person · Walking Simulator · Indie

Quern - Undying Thoughts
Shared: First-Person · Puzzle · Walking Simulator

