Games like Escape the Lab
Games like Escape the Lab include Kerbal Space Program, Garry's Mod, Goat Simulator, Universe Sandbox, and BONEWORKS. We matched them by the tags players give Escape the Lab on Steam (Casual, Simulation, Indie, Education, and Escape Room): closest matches first, and among equally close ones the better-known games.

Kerbal Space Program
Shared: Simulation · Science · Indie

Garry's Mod
Shared: Casual · Sandbox · Simulation

Goat Simulator
Shared: Simulation · Casual · Indie

Universe Sandbox
Shared: Simulation · Casual · Indie

BONEWORKS
Shared: VR · Action · Simulation

House Flipper
Shared: Simulation · Casual · Indie

SPORE™
Shared: Simulation · Casual · Sandbox

Universe Sandbox
Shared: Simulation · Science · Sandbox

Barn Finders
Shared: Casual · Simulation · Indie

Slime Rancher
Shared: Simulation · Casual · Exploration

while True: learn()
Shared: Simulation · Education · Indie

PC Building Simulator
Shared: Simulation · Education · Casual

BONELAB
Shared: VR · Action · Sandbox

Totally Accurate Battle Simulator
Shared: Simulation · Indie · Sandbox

Poly Bridge
Shared: Simulation · Indie · Puzzle

Surgeon Simulator
Shared: Simulation · Indie · VR

Wobbly Life
Shared: Simulation · Casual · Indie

Game Dev Tycoon
Shared: Simulation · Indie · Casual

Hard Bullet
Shared: VR · Simulation · Indie

Electrician Simulator
Shared: Simulation · Education · Indie

Human Resource Machine
Shared: Casual · Indie · Simulation

Hot Dogs, Horseshoes & Hand Grenades
Shared: VR · Simulation · Sandbox

Escape Simulator
Shared: Escape Room · Puzzle · Simulation

Elite Dangerous
Shared: Simulation · VR · Exploration

