Games like Elixir
Games like Elixir include Papers, Please, Strange Horticulture, Gorogoa, There Is No Game: Wrong Dimension, and Potion Craft: Alchemist Simulator. We matched them by the tags players give Elixir on Steam (Exploration, Medical Sim, Puzzle, Crafting, and Investigation): closest matches first, and among equally close ones the better-known games.

Papers, Please
Shared: Point & Click · Puzzle · Simulation

Strange Horticulture
Shared: Puzzle · Investigation · Exploration

Gorogoa
Shared: Puzzle · Point & Click · Hand-drawn

There Is No Game: Wrong Dimension
Shared: Puzzle · Point & Click · Indie

Potion Craft: Alchemist Simulator
Shared: Crafting · Medieval · Simulation

Blue Prince
Shared: Exploration · Puzzle · Investigation

Terraria
Shared: Crafting · Exploration · 2D

Machinarium
Shared: Puzzle · Point & Click · 2D

Strange Antiquities
Shared: Puzzle · Exploration · Point & Click

FEZ
Shared: Puzzle · Exploration · Indie

DAVE THE DIVER
Shared: Exploration · Casual · Pixel Graphics

ANIMAL WELL
Shared: Exploration · Puzzle · 2D

The House of Da Vinci
Shared: Puzzle · Exploration · Point & Click

Pentiment
Shared: Investigation · Exploration · Adventure

OneShot
Shared: Puzzle · Exploration · Pixel Graphics

Chants of Sennaar
Shared: Puzzle · Point & Click · Exploration

No Case Should Remain Unsolved
Shared: Puzzle · Investigation · Point & Click

Endacopia
Shared: Point & Click · Puzzle · Exploration

Graveyard Keeper
Shared: Crafting · Medieval · Simulation

Carto
Shared: Exploration · Puzzle · Indie

Desktop Explorer
Shared: Puzzle · Investigation · Point & Click

The Case of the Golden Idol
Shared: Puzzle · Investigation · Point & Click

Submachine: Legacy
Shared: Puzzle · Exploration · Point & Click

Storyteller
Shared: Puzzle · Point & Click · 2D