Games like Dyson Sphere: Desktop Factory
Games like Dyson Sphere: Desktop Factory include Factorio, Dyson Sphere Program, shapez, Oxygen Not Included, and Prison Architect. We matched them by the tags players give Dyson Sphere: Desktop Factory on Steam (Casual, Automation, Building, Simulation, and Idler): closest matches first, and among equally close ones the better-known games.

Factorio
Shared: Automation · Strategy · Base Building

Dyson Sphere Program
Shared: Automation · Building · Simulation

shapez
Shared: Automation · Building · Strategy

Oxygen Not Included
Shared: Building · Base Building · Simulation

Prison Architect
Shared: Building · Simulation · Sandbox

Cities: Skylines
Shared: Building · Simulation · Strategy

Beltmatic
Shared: Casual · Automation · Simulation

Rusty's Retirement
Shared: Automation · Idler · Simulation

Satisfactory
Shared: Automation · Building · Base Building

shapez 2 - Factory
Shared: Automation · Building · Simulation

Hydroneer
Shared: Automation · Building · Base Building

Mindustry
Shared: Automation · Building · Strategy

Cookie Clicker
Shared: Casual · Idler · Incremental

Cities: Skylines II
Shared: Building · Simulation · Sandbox

Nodebuster
Shared: Casual · Simulation · Idler

Shelldiver
Shared: Casual · Incremental · Idler

Jurassic World Evolution
Shared: Building · Simulation · Strategy

Garry's Mod
Shared: Building · Casual · Sandbox

Starvester
Shared: Automation · Idler · Casual

Alchemy Factory
Shared: Automation · Building · Casual

(the) Gnorp Apologue
Shared: Building · Idler · Incremental

Manor Lords
Shared: Simulation · Strategy · Building

Captain of Industry
Shared: Automation · Simulation · Building

Fortune Mill
Shared: Automation · Idler · Casual