Games like Destroy Space Aliens
Games like Destroy Space Aliens include Hollow Knight, Dust: An Elysian Tail, Ori and the Will of the Wisps, Hollow Knight: Silksong, and Rogue Legacy 2. We matched them by the tags players give Destroy Space Aliens on Steam (Action, Adventure, Indie, Metroidvania, and Platformer): closest matches first, and among equally close ones the better-known games.

Hollow Knight
Shared: Metroidvania · Platformer · Indie

Dust: An Elysian Tail
Shared: Action · Indie · Metroidvania

Ori and the Will of the Wisps
Shared: Metroidvania · Action · Platformer

Hollow Knight: Silksong
Shared: Metroidvania · Indie · Platformer

Rogue Legacy 2
Shared: Action · Metroidvania · Indie

Nine Sols
Shared: Metroidvania · Action · Platformer

Skul: The Hero Slayer
Shared: Action · Indie · Platformer

SteamWorld Dig 2
Shared: Adventure · Action · Indie

Gato Roboto
Shared: Action · Indie · Metroidvania

Axiom Verge
Shared: Indie · Metroidvania · Action

F.I.S.T.: Forged In Shadow Torch
Shared: Action · Metroidvania · Adventure

Monster Boy and the Cursed Kingdom
Shared: Action · Adventure · Indie

Bloodstained: Ritual of the Night
Shared: Action · Metroidvania · Adventure

Guacamelee! Gold Edition
Shared: Action · Metroidvania · Indie

Dead Cells
Shared: Adventure · Metroidvania · Action

UnEpic
Shared: Indie · Action · Metroidvania

Iconoclasts
Shared: Indie · Action · Metroidvania

Blasphemous
Shared: Metroidvania · Indie · Action

Wonder Boy: The Dragon's Trap
Shared: Adventure · Action · Platformer

Ghost 1.0
Shared: Action · Indie · Metroidvania

Rogue Legacy
Shared: Indie · Action · Platformer

Owlboy
Shared: Adventure · Indie · Metroidvania

Constance
Shared: Action · Metroidvania · Platformer

Apotheon
Shared: Action · Adventure · Metroidvania