Games like Destination Sol
Games like Destination Sol include Endless Sky, Once Human, Halo Infinite, Star Trek Online, and Warframe. We matched them by the tags players give Destination Sol on Steam (Free to Play, RPG, Indie, Action, and Space): closest matches first, and among equally close ones the better-known games.

Endless Sky
Shared: Free to Play · Space · Open World

Once Human
Shared: Free to Play · Open World · Action

Halo Infinite
Shared: Free to Play · Action · Singleplayer

Star Trek Online
Shared: Free to Play · RPG · Space

Warframe
Shared: Free to Play · RPG · Action

The Binding of Isaac: Rebirth
Shared: Indie · Roguelike · Replay Value

FTL: Faster Than Light
Shared: Space · Indie · Singleplayer

Where Winds Meet
Shared: Free to Play · Open World · Singleplayer

No Man's Sky
Shared: Space · Open World · Procedural Generation

Trove
Shared: Free to Play · Open World · RPG

Terraria
Shared: 2D · Indie · Open World

The Binding of Isaac
Shared: Indie · Action · Roguelike

Wuthering Waves
Shared: Free to Play · Open World · Action

Vampire Survivors
Shared: Indie · 2D · Singleplayer

Rogue Legacy 2
Shared: Action · Indie · Arcade

Monster Hunter: World
Shared: Action · RPG · Open World

Starfield
Shared: RPG · Space · Open World

Noita
Shared: Indie · 2D · Open World

Skul: The Hero Slayer
Shared: Indie · Action · 2D

Mount & Blade II: Bannerlord
Shared: RPG · Open World · Action

ELDEN RING
Shared: RPG · Open World · Action