Games like Desktop Immortal
Games like Desktop Immortal include The Sims™ 4, Disney Dreamlight Valley, Stardew Valley, Slime Rancher, and Cookie Clicker. We matched them by the tags players give Desktop Immortal on Steam (Casual, Simulation, Sandbox, Life Sim, and Idler): closest matches first, and among equally close ones the better-known games.

The Sims™ 4
Shared: Life Sim · Simulation · Sandbox

Disney Dreamlight Valley
Shared: Life Sim · Simulation · Exploration

Stardew Valley
Shared: Life Sim · Simulation · Sandbox

Slime Rancher
Shared: Exploration · Cute · Sandbox

Cookie Clicker
Shared: Casual · Idler · Incremental

Two Point Museum
Shared: Casual · Simulation · Sandbox

Shelldiver
Shared: Casual · Incremental · Idler

MyVoiceZoo
Shared: Casual · Simulation · Sandbox

Nodebuster
Shared: Casual · Simulation · Incremental

SPORE™
Shared: Sandbox · Simulation · Casual

The Sims™ 3
Shared: Simulation · Life Sim · Sandbox

Paralives
Shared: Simulation · Life Sim · Sandbox

Digseum
Shared: Casual · Simulation · Idler

Starsand Island
Shared: Life Sim · Casual · Sandbox

Tiny Pasture
Shared: Idler · Casual · Incremental

Garry's Mod
Shared: Sandbox · Casual · Simulation

Potion Craft: Alchemist Simulator
Shared: Simulation · Casual · Sandbox

BidKing
Shared: Casual · Simulation · Life Sim

Maltese's Fluffy Onsen
Shared: Simulation · Casual · Idler

Cell to Singularity - Evolution Never Ends
Shared: Simulation · Casual · Incremental

Goat Simulator
Shared: Simulation · Sandbox · Casual

Growtopia
Shared: Casual · Simulation · Sandbox

Unpacking
Shared: Casual · Simulation · Cute

Forage Wizard
Shared: Casual · Simulation · Sandbox