Games like Desktop Friend
Games like Desktop Friend include Stardew Valley, Banana, Bongo Cat, Unpacking, and Cookie Clicker. We matched them by the tags players give Desktop Friend on Steam (Casual, Simulation, Life Sim, Incremental, and Creature Collector): closest matches first, and among equally close ones the better-known games.

Stardew Valley
Shared: Life Sim · Simulation · Pixel Graphics

Banana
Shared: Incremental · Casual · 2D

Bongo Cat
Shared: Casual · Cute · Cats

Unpacking
Shared: Casual · Cute · Simulation

Cookie Clicker
Shared: Casual · Incremental · Pixel Graphics

Tiny Pasture
Shared: Casual · Incremental · Cute

Shelldiver
Shared: Casual · Incremental · Simulation

Minami Lane
Shared: Casual · Life Sim · Simulation

DAVE THE DIVER
Shared: Casual · Pixel Graphics · Management

The Sims™ 4
Shared: Life Sim · Simulation · Casual

Nodebuster
Shared: Casual · Incremental · Simulation

Little Witch in the Woods
Shared: Casual · Life Sim · Simulation

Digseum
Shared: Casual · Incremental · Simulation

Screen Cat
Shared: Casual · Life Sim · Cute

Sticky Business
Shared: Casual · Simulation · Cute

Potion Craft: Alchemist Simulator
Shared: Simulation · Casual · 2D

Paralives
Shared: Life Sim · Simulation · Casual

Maltese's Fluffy Onsen
Shared: Simulation · Casual · Pixel Graphics

Cornerpond
Shared: Simulation · Incremental · Casual

Slime Rancher 2
Shared: Cute · Simulation · Creature Collector

Youtubers Life
Shared: Life Sim · Casual · Simulation

Russian Life Simulator
Shared: Simulation · Incremental · 2D

Game Dev Tycoon
Shared: Simulation · Casual · Management

Calico
Shared: Casual · Simulation · Cute