Games like Depopulation
Games like Depopulation include Crusader Kings III, The Scroll of Taiwu : Beyond The Dome, Mini Motorways, BidKing, and Plague Inc: Evolved. We matched them by the tags players give Depopulation on Steam (Casual, Simulation, Strategy, and RPG): closest matches first, and among equally close ones the better-known games.

Crusader Kings III
Shared: Strategy · Simulation · RPG

The Scroll of Taiwu : Beyond The Dome
Shared: RPG · Strategy · Simulation

Mini Motorways
Shared: Simulation · Casual · Strategy

BidKing
Shared: Casual · Strategy · Simulation

Plague Inc: Evolved
Shared: Simulation · Strategy · Casual

Plebby Quest: The Crusades
Shared: Casual · Strategy · Simulation

Chinese Parents
Shared: Simulation · Casual · RPG

Game Dev Tycoon
Shared: Simulation · Casual · Strategy

Touhou Mystia's Izakaya
Shared: Casual · Simulation · RPG

Dragon Cliff
Shared: Strategy · RPG · Casual

Retirement Simulator
Shared: Simulation · RPG · Casual

Mount & Blade II: Bannerlord
Shared: Strategy · RPG · Simulation

Home Behind
Shared: RPG · Casual · Simulation

Total War: WARHAMMER
Shared: Simulation · Strategy · RPG

Dead Age
Shared: RPG · Strategy · Casual

Two Point Museum
Shared: Casual · Simulation · Strategy

Cities: Skylines
Shared: Simulation · Strategy · Casual

Crusader Kings II
Shared: Strategy · Simulation · RPG

Nodebuster
Shared: Casual · Strategy · Simulation

911 Operator
Shared: Simulation · Strategy · Casual

Heroes of Might and Magic: Olden Era
Shared: Strategy · RPG · Simulation

No-brainer Heroes 挂机吧!勇者
Shared: Casual · Strategy · RPG

Amazing Cultivation Simulator
Shared: Simulation · RPG · Strategy

SPORE™
Shared: Simulation · Casual · Strategy