Games like Demon Hunter 5: Ascendance
Games like Demon Hunter 5: Ascendance include The Room, The Room Two, The Room 4: Old Sins, The Room Three, and Gorogoa. We matched them by the tags players give Demon Hunter 5: Ascendance on Steam (Adventure, Casual, Hidden Object, Investigation, and Puzzle): closest matches first, and among equally close ones the better-known games.

The Room
Shared: Adventure · Puzzle · Hidden Object

The Room Two
Shared: Puzzle · Hidden Object · Adventure

The Room 4: Old Sins
Shared: Adventure · Puzzle · Hidden Object

The Room Three
Shared: Adventure · Puzzle · Hidden Object

Gorogoa
Shared: Puzzle · Casual · Adventure

Rusty Lake Paradise
Shared: Adventure · Puzzle · Horror

Enigmatis 2: The Mists of Ravenwood
Shared: Adventure · Hidden Object · Casual

Frankenstein: Master of Death
Shared: Hidden Object · Casual · Adventure

The House of Da Vinci
Shared: Hidden Object · Puzzle · Adventure

Servant of the Lake
Shared: Adventure · Puzzle · Atmospheric

Enigmatis: The Ghosts of Maple Creek
Shared: Adventure · Hidden Object · Casual

Morphopolis
Shared: Hidden Object · Casual · Adventure

The Death Game Report
Shared: Adventure · Casual · Puzzle

Boxes: Lost Fragments
Shared: Adventure · Casual · Puzzle

Sally Face - Episode One
Shared: Adventure · Horror · Puzzle

Sinister City
Shared: Adventure · Hidden Object · Casual

Hidden Folks
Shared: Casual · Hidden Object · Puzzle

Machinarium
Shared: Puzzle · Adventure · Casual

Abyss: The Wraiths of Eden
Shared: Casual · Adventure · Hidden Object

Storyteller
Shared: Adventure · Puzzle · 2D

The Rewinder
Shared: Adventure · Puzzle · Mystery

9 Clues: The Secret of Serpent Creek
Shared: Casual · Adventure · Hidden Object

9 Clues 2: The Ward
Shared: Adventure · Hidden Object · Casual

The Room VR: A Dark Matter
Shared: Adventure · Puzzle · Investigation