Games like City Z
Games like City Z include The Binding of Isaac, Hotline Miami, RUINER, The Binding of Isaac: Rebirth, and Hotline Miami 2: Wrong Number. We matched them by the tags players give City Z on Steam (Indie, Zombies, Top-Down Shooter, Procedural Generation, and Twin Stick Shooter): closest matches first, and among equally close ones the better-known games.

The Binding of Isaac
Shared: Indie · Procedural Generation · Difficult

Hotline Miami
Shared: Indie · Action · Top-Down

RUINER
Shared: Top-Down Shooter · Indie · Action

The Binding of Isaac: Rebirth
Shared: Indie · Difficult · Replay Value

Hotline Miami 2: Wrong Number
Shared: Indie · Great Soundtrack · Action

Splatter - Zombiecalypse Now
Shared: Zombies · Top-Down Shooter · Indie

SYNTHETIK: Legion Rising
Shared: Indie · Top-Down Shooter · Action

Hollow Knight: Silksong
Shared: Indie · Difficult · Singleplayer

Yet Another Zombie Survivors
Shared: Zombies · Top-Down Shooter · Indie

Nation Red
Shared: Zombies · Indie · Top-Down Shooter

The Last Stand: Aftermath
Shared: Zombies · Top-Down Shooter · Singleplayer

Hades
Shared: Indie · Action · Singleplayer

Nuclear Throne
Shared: Indie · Top-Down Shooter · Difficult

FTL: Faster Than Light
Shared: Indie · Singleplayer · Procedural Generation

Hollow Knight
Shared: Indie · Difficult · Singleplayer

Halo: Spartan Assault
Shared: Top-Down Shooter · Action · Top-Down

UBERMOSH
Shared: Indie · Action · Great Soundtrack

Hyper Light Drifter
Shared: Indie · Great Soundtrack · Action

Super Hexagon
Shared: Indie · Difficult · Great Soundtrack

12 is Better Than 6
Shared: Top-Down Shooter · Indie · Action

Celeste
Shared: Indie · Difficult · Great Soundtrack

Nex Machina
Shared: Twin Stick Shooter · Indie · Action

Geometry Dash
Shared: Difficult · Great Soundtrack · Singleplayer

Blackout Z: Slaughterhouse Edition
Shared: Indie · Top-Down Shooter · Zombies