Games like Cardiac Powder
Games like Cardiac Powder include Hotline Miami, Hotline Miami 2: Wrong Number, RUINER, 12 is Better Than 6, and The Hong Kong Massacre. We matched them by the tags players give Cardiac Powder on Steam (Action, Singleplayer, Indie, Difficult, and Adventure): closest matches first, and among equally close ones the better-known games.

Hotline Miami
Shared: Action · Indie · Top-Down

Hotline Miami 2: Wrong Number
Shared: Action · Difficult · Indie

RUINER
Shared: Action · Indie · Top-Down Shooter

12 is Better Than 6
Shared: Action · Singleplayer · Indie

The Hong Kong Massacre
Shared: Action · Indie · Top-Down Shooter

Hyper Light Drifter
Shared: Indie · Action · Adventure

Hollow Knight: Silksong
Shared: Indie · Difficult · Singleplayer

BioShock Infinite
Shared: Action · Singleplayer · Shooter

My Friend Pedro
Shared: Action · Indie · Singleplayer

Ape Out
Shared: Indie · Action · Singleplayer

Hollow Knight
Shared: Difficult · Indie · Singleplayer

DOOM Eternal
Shared: Action · Singleplayer · Gore

SUPERHOT
Shared: Action · Indie · Singleplayer

Titan Souls
Shared: Indie · Difficult · Action

Red Dead Redemption 2
Shared: Action · Adventure · Singleplayer

Trepang2
Shared: Singleplayer · Action · Shooter

God of War
Shared: Action · Singleplayer · Adventure

Grand Theft Auto V Legacy
Shared: Action · Singleplayer · Adventure

SYNTHETIK: Legion Rising
Shared: Action · Indie · Top-Down Shooter

Halo: Spartan Assault
Shared: Action · Singleplayer · Top-Down Shooter

The Binding of Isaac
Shared: Indie · Difficult · Action

Tomb Raider Game of the Year
Shared: Action · Adventure · Singleplayer

Half-Life 2
Shared: Action · Singleplayer · Adventure

Serious Sam 4
Shared: Action · Singleplayer · Adventure