Games like Buttons Up! 2
Games like Buttons Up! 2 include Factorio, They Are Billions, Oxygen Not Included, Frostpunk, and This War of Mine. We matched them by the tags players give Buttons Up! 2 on Steam (Strategy, Survival, RTS, Incremental, and Tactical): closest matches first, and among equally close ones the better-known games.
Factorio
Shared: Strategy · Resource Management · Survival
They Are Billions
Shared: Strategy · Survival · RTS
Oxygen Not Included
Shared: Survival · Resource Management · Strategy
Frostpunk
Shared: Survival · Strategy · Resource Management
This War of Mine
Shared: Survival · Strategy · Singleplayer
Cartel Tycoon
Shared: RTS · Survival · Strategy
RimWorld
Shared: Survival · Strategy · Management
Cities: Skylines
Shared: Strategy · Management · Building
Kingdoms and Castles
Shared: Strategy · Resource Management · Management
Manor Lords
Shared: Strategy · Management · Resource Management
Age of Empires II (Retired)
Shared: Strategy · RTS · Resource Management
The Alters
Shared: Survival · Strategy · Management
Aliens: Dark Descent
Shared: Strategy · RTS · Tactical
Going Medieval
Shared: Strategy · Survival · Management
Farthest Frontier
Shared: Strategy · Resource Management · Building
Banished
Shared: Strategy · Survival · Singleplayer
Creeper World 3: Arc Eternal
Shared: Strategy · RTS · Singleplayer
Against the Storm
Shared: Strategy · Management · Resource Management
Sheltered
Shared: Survival · Strategy · Resource Management
Cookie Clicker
Shared: Incremental · Management · Strategy
Startup Company
Shared: Strategy · Management · Singleplayer
Prison Architect
Shared: Strategy · Management · Building
IXION
Shared: Strategy · Survival · Resource Management
Company of Heroes 2
Shared: Strategy · RTS · Tactical