Games like Breakthrough
Games like Breakthrough include The Binding of Isaac: Rebirth, Enter the Gungeon, The Binding of Isaac, Nuclear Throne, and Vampire Survivors. We matched them by the tags players give Breakthrough on Steam (Roguelike, Difficult, Indie, Top-Down Shooter, and Bullet Hell): closest matches first, and among equally close ones the better-known games.

The Binding of Isaac: Rebirth
Shared: Roguelike · Indie · Difficult

Enter the Gungeon
Shared: Roguelike · Bullet Hell · Difficult

The Binding of Isaac
Shared: Roguelike · Indie · Difficult

Nuclear Throne
Shared: Roguelike · Indie · Difficult

Vampire Survivors
Shared: Bullet Hell · Action Roguelike · Indie

Skul: The Hero Slayer
Shared: Indie · Roguelike · Action Roguelike

SYNTHETIK: Legion Rising
Shared: Top-Down Shooter · Indie · Difficult

Spelunky
Shared: Roguelike · Indie · Difficult

Brotato
Shared: Roguelike · Bullet Hell · Action Roguelike

Tiny Rogues
Shared: Difficult · Bullet Hell · Top-Down Shooter

Megabonk
Shared: Roguelike · Indie · Action Roguelike

Dead Estate
Shared: Roguelike · Difficult · Action Roguelike

Voidigo
Shared: Roguelike · Twin Stick Shooter · Action Roguelike

BALL x PIT
Shared: Roguelike · Bullet Hell · Action

Pathogenic
Shared: Roguelike · Top-Down Shooter · Bullet Hell

Hades
Shared: Indie · Roguelike · Action Roguelike

Noita
Shared: Roguelike · Difficult · Indie

Risk of Rain (2013)
Shared: Roguelike · Indie · Action Roguelike

Star of Providence
Shared: Bullet Hell · Indie · Difficult

Hotline Miami 2: Wrong Number
Shared: Gore · Difficult · Indie

Rabbit and Steel
Shared: Roguelike · Bullet Hell · Difficult

Dungreed
Shared: Roguelike · Indie · Action Roguelike

Galactic Glitch
Shared: Roguelike · Difficult · Top-Down Shooter

Hotline Miami
Shared: Indie · Action · Gore