Games like Blood in the Panopticon
Games like Blood in the Panopticon include Hades, Hades II, Vampire Survivors, Death Must Die, and Halls of Torment. We matched them by the tags players give Blood in the Panopticon on Steam (Action Roguelike, Hack and Slash, Twin Stick Shooter, Shoot 'Em Up, and Story Rich): closest matches first, and among equally close ones the better-known games.

Hades
Shared: Action Roguelike · Hack and Slash · Roguelite

Hades II
Shared: Hack and Slash · Action Roguelike · Roguelite

Vampire Survivors
Shared: Action Roguelike · Bullet Hell · Roguelite

Death Must Die
Shared: Action Roguelike · Hack and Slash · Bullet Hell

Halls of Torment
Shared: Action Roguelike · Bullet Hell · Roguelite

Enter the Gungeon
Shared: Action Roguelike · Bullet Hell · Twin Stick Shooter

20 Minutes Till Dawn
Shared: Action Roguelike · Shoot 'Em Up · Bullet Hell

Rogue: Genesia
Shared: Action Roguelike · Twin Stick Shooter · Bullet Hell

Soulstone Survivors
Shared: Action Roguelike · Bullet Hell · Hack and Slash

Hero Siege
Shared: Hack and Slash · Action Roguelike · RPG

NieR:Automata™
Shared: Hack and Slash · Story Rich · RPG

BALL x PIT
Shared: Action Roguelike · Shoot 'Em Up · Bullet Hell

Skul: The Hero Slayer
Shared: Action Roguelike · Roguelite · Indie

Dead Cells
Shared: Action Roguelike · Hack and Slash · Roguelite

Voidigo
Shared: Action Roguelike · Twin Stick Shooter · Shoot 'Em Up

Megabonk
Shared: Action Roguelike · Bullet Hell · Roguelite

Star of Providence
Shared: Action Roguelike · Shoot 'Em Up · Bullet Hell

Nova Drift
Shared: Shoot 'Em Up · Action Roguelike · Bullet Hell

Tower of Babel: Survivors of Chaos
Shared: Action Roguelike · Bullet Hell · Hack and Slash

Undertale
Shared: Story Rich · Choices Matter · Bullet Hell

Time Wasters
Shared: Action Roguelike · Twin Stick Shooter · Bullet Hell

Realm of Ink
Shared: Action Roguelike · Hack and Slash · Roguelite

暖雪 Warm Snow
Shared: Action Roguelike · Roguelite · Story Rich

Brotato
Shared: Action Roguelike · Bullet Hell · Hack and Slash