Games like Bioframe Outpost
Games like Bioframe Outpost include Outer Wilds, Hollow Knight, Hollow Knight: Silksong, Ori and the Will of the Wisps, and The Swapper. We matched them by the tags players give Bioframe Outpost on Steam (Metroidvania, Exploration, Puzzle, Sci-fi, and Atmospheric): closest matches first, and among equally close ones the better-known games.

Outer Wilds
Shared: Exploration · Space · Puzzle

Hollow Knight
Shared: Metroidvania · Exploration · 2D

Hollow Knight: Silksong
Shared: Metroidvania · Exploration · 2D

Ori and the Will of the Wisps
Shared: Metroidvania · Exploration · Atmospheric

The Swapper
Shared: Puzzle · Sci-fi · Atmospheric

ANIMAL WELL
Shared: Metroidvania · Exploration · Puzzle

Deliver Us The Moon
Shared: Sci-fi · Adventure · Space

Stray
Shared: Atmospheric · Exploration · Adventure

No Man's Sky
Shared: Exploration · Space · Sci-fi

COCOON
Shared: Exploration · Puzzle · Adventure

The Talos Principle
Shared: Puzzle · Sci-fi · Atmospheric

Starfield
Shared: Space · Exploration · Sci-fi

STAR WARS Jedi: Fallen Order™
Shared: Exploration · Sci-fi · Action-Adventure

Prey
Shared: Sci-fi · Space · Atmospheric

MIO: Memories in Orbit
Shared: Metroidvania · Exploration · Atmospheric

FAR: Lone Sails
Shared: Atmospheric · Exploration · Adventure

TUNIC
Shared: Exploration · Puzzle · Metroidvania

OneShot
Shared: Puzzle · Atmospheric · Indie

Rain World
Shared: Exploration · Atmospheric · 2D

Axiom Verge
Shared: Metroidvania · Sci-fi · Indie

Insanely Twisted Shadow Planet
Shared: Metroidvania · Exploration · Adventure

Nine Sols
Shared: Metroidvania · 2D · Atmospheric

Chants of Sennaar
Shared: Puzzle · Adventure · Atmospheric

Cosmoteer: Starship Architect & Commander
Shared: Sci-fi · Space · Exploration