Games like Automation Empire
Games like Automation Empire include Factorio, Cities: Skylines, Dyson Sphere Program, Prison Architect, and Captain of Industry. We matched them by the tags players give Automation Empire on Steam (Simulation, Automation, Strategy, Base Building, and Sandbox): closest matches first, and among equally close ones the better-known games.

Factorio
Shared: Automation · Base Building · Sandbox

Cities: Skylines
Shared: Simulation · Strategy · Building

Dyson Sphere Program
Shared: Automation · Base Building · Simulation

Prison Architect
Shared: Simulation · Base Building · Sandbox

Captain of Industry
Shared: Automation · Simulation · Base Building

Manor Lords
Shared: Simulation · Strategy · Base Building

Cities: Skylines II
Shared: Simulation · Sandbox · Building

shapez
Shared: Automation · Base Building · Sandbox

Kingdoms and Castles
Shared: Simulation · Strategy · Resource Management

Against the Storm
Shared: Simulation · Strategy · Base Building

Satisfactory
Shared: Automation · Base Building · Building

Oxygen Not Included
Shared: Base Building · Building · Resource Management

Jurassic World Evolution
Shared: Simulation · Building · Strategy

Foundation
Shared: Simulation · Strategy · Sandbox

Jurassic World Evolution 2
Shared: Simulation · Building · Sandbox

Workers & Resources: Soviet Republic
Shared: Simulation · Strategy · Base Building

Transport Fever 2
Shared: Simulation · Strategy · Management

Factory Town
Shared: Automation · Base Building · Resource Management

Empires of the Undergrowth
Shared: Simulation · Strategy · Base Building

Production Line : Car factory simulation
Shared: Simulation · Strategy · Automation

Little Big Workshop
Shared: Simulation · Strategy · Automation

shapez 2 - Factory
Shared: Automation · Strategy · Simulation

Planet Zoo
Shared: Simulation · Management · Sandbox

RimWorld
Shared: Base Building · Strategy · Sandbox