Games like Ascend Factory
Games like Ascend Factory include Dyson Sphere Program, shapez 2 - Factory, Factorio, shapez, and Oxygen Not Included. We matched them by the tags players give Ascend Factory on Steam (Automation, Strategy, Puzzle, Building, and Logic): closest matches first, and among equally close ones the better-known games.

Dyson Sphere Program
Shared: Automation · Building · Base Building

shapez 2 - Factory
Shared: Automation · Strategy · Building

Factorio
Shared: Automation · Strategy · Base Building

shapez
Shared: Automation · Strategy · Base Building

Oxygen Not Included
Shared: Building · Base Building · Strategy

Captain of Industry
Shared: Automation · Strategy · Simulation

Cities: Skylines
Shared: Building · Strategy · Simulation

Prison Architect
Shared: Building · Simulation · Strategy

Manor Lords
Shared: Strategy · Simulation · Base Building

Satisfactory
Shared: Automation · Base Building · Building

Against the Storm
Shared: Strategy · Simulation · Building

Mini Motorways
Shared: Strategy · Simulation · Puzzle

Automation Empire
Shared: Automation · Strategy · Simulation

Little Big Workshop
Shared: Strategy · Simulation · Building

Production Line : Car factory simulation
Shared: Strategy · Automation · Simulation

Mindustry
Shared: Automation · Strategy · Base Building

RimWorld
Shared: Strategy · Base Building · Simulation

Jurassic World Evolution
Shared: Building · Strategy · Simulation

Cities: Skylines II
Shared: Building · Simulation · Strategy

Jurassic World Evolution 2
Shared: Building · Strategy · Simulation

Workers & Resources: Soviet Republic
Shared: Strategy · Simulation · Building

MineMogul
Shared: Automation · Building · Strategy

Timberborn
Shared: Automation · Building · Strategy

Empires of the Undergrowth
Shared: Strategy · Simulation · Base Building