Games like Artificial Extinction
Games like Artificial Extinction include BioShock Infinite, Mount & Blade II: Bannerlord, Fallout 4, Freeman: Guerrilla Warfare, and Sanctum 2. We matched them by the tags players give Artificial Extinction on Steam (Action, Adventure, Indie, Strategy, and Tower Defense): closest matches first, and among equally close ones the better-known games.

BioShock Infinite
Shared: Action · First-Person · Adventure

Mount & Blade II: Bannerlord
Shared: Strategy · RPG · Action

Fallout 4
Shared: Adventure · RPG · Action

Freeman: Guerrilla Warfare
Shared: Action · Strategy · RPG

Sanctum 2
Shared: Action · Tower Defense · Strategy

Half-Life 2
Shared: Action · FPS · Sci-fi

Rust
Shared: Adventure · Survival · Action

Mount & Blade: Warband
Shared: Strategy · RPG · Action

Fallout: New Vegas
Shared: RPG · Action · Adventure

PUBG: BATTLEGROUNDS
Shared: Action · Survival · FPS

Black Mesa
Shared: Action · FPS · First-Person

Dungeon of the ENDLESS™
Shared: Strategy · Indie · Tower Defense

Orcs Must Die! 2
Shared: Action · Tower Defense · Strategy

Far Cry 3
Shared: Action · Adventure · FPS

Atomic Heart
Shared: Adventure · Action · FPS

Far Cry® Primal
Shared: Action · Adventure · First-Person

Cyberpunk 2077
Shared: RPG · Sci-fi · FPS

Sanctum
Shared: Action · Tower Defense · Strategy

Polarity
Shared: Indie · Adventure · First-Person

S.T.A.L.K.E.R. 2: Heart of Chornobyl - Standard Edition
Shared: FPS · Survival · Action

ORION: Prelude
Shared: Action · Adventure · Indie

Don't Starve Together
Shared: Adventure · Survival · Indie

RoboCop: Rogue City
Shared: Action · FPS · First-Person

The Escapists
Shared: Strategy · Action · Indie