Games like Amerzone: The Explorer’s Legacy (1999)
Games like Amerzone: The Explorer’s Legacy (1999) include The Room, The Room Two, The Room 4: Old Sins, Chants of Sennaar, and The Room Three. We matched them by the tags players give Amerzone: The Explorer’s Legacy (1999) on Steam (Adventure, Point & Click, Casual, First-Person, and Puzzle): closest matches first, and among equally close ones the better-known games.

The Room
Shared: Point & Click · Puzzle · Adventure

The Room Two
Shared: Point & Click · Puzzle · Adventure

The Room 4: Old Sins
Shared: Point & Click · Adventure · Puzzle

Chants of Sennaar
Shared: Adventure · Puzzle · Point & Click

The Room Three
Shared: Adventure · Point & Click · Puzzle

Gorogoa
Shared: Puzzle · Casual · Point & Click

A Story About My Uncle
Shared: Adventure · First-Person · Singleplayer

Myst: Masterpiece Edition
Shared: Adventure · Point & Click · Casual

There Is No Game: Wrong Dimension
Shared: Point & Click · Adventure · Puzzle

Boxes: Lost Fragments
Shared: Point & Click · Adventure · Puzzle

Syberia
Shared: Adventure · Point & Click · Casual

Firewatch
Shared: Adventure · Atmospheric · First-Person

Portal 2
Shared: Singleplayer · First-Person · Puzzle

Machinarium
Shared: Point & Click · Puzzle · Adventure

Riven (1997)
Shared: Adventure · Point & Click · Puzzle

Poppy Playtime
Shared: Singleplayer · First-Person · Puzzle

Moncage
Shared: Casual · Adventure · Puzzle

Monument Valley
Shared: Adventure · Puzzle · Casual

Stray
Shared: Adventure · Singleplayer · Atmospheric

The Witness
Shared: Puzzle · First-Person · Singleplayer

The Mr. Rabbit Magic Show
Shared: Adventure · Point & Click · Puzzle

The Talos Principle
Shared: Puzzle · First-Person · Singleplayer

Iris.Fall
Shared: Adventure · Casual · Puzzle

FORM
Shared: Point & Click · Adventure · Singleplayer