Games like Amatsuko
Games like Amatsuko include Outer Wilds, Firewatch, What Remains of Edith Finch, Blue Prince, and The Room 4: Old Sins. We matched them by the tags players give Amatsuko on Steam (Adventure, Exploration, Mystery, Story Rich, and Puzzle): closest matches first, and among equally close ones the better-known games.

Outer Wilds
Shared: Exploration · Mystery · Adventure

Firewatch
Shared: Adventure · Story Rich · Mystery

What Remains of Edith Finch
Shared: Story Rich · Mystery · Exploration

Blue Prince
Shared: Exploration · Mystery · Puzzle

The Room 4: Old Sins
Shared: Mystery · Adventure · Puzzle

Sally Face - Episode One
Shared: Story Rich · Adventure · Indie

The Room Three
Shared: Adventure · Mystery · Puzzle

Stray
Shared: Adventure · Exploration · Singleplayer

Poppy Playtime
Shared: Singleplayer · Puzzle · Mystery

DREDGE
Shared: Exploration · Adventure · Mystery

SOMA
Shared: Story Rich · Exploration · Horror

Return of the Obra Dinn
Shared: Mystery · Story Rich · Puzzle

Little Nightmares II
Shared: Adventure · Puzzle · Singleplayer

Rise of the Tomb Raider™
Shared: Adventure · Exploration · Singleplayer

The Room
Shared: Mystery · Puzzle · Adventure

Amnesia: Rebirth
Shared: Story Rich · Puzzle · Adventure

The Witness
Shared: Exploration · Puzzle · Singleplayer

INFRA
Shared: Exploration · Puzzle · Adventure

Fallout 4
Shared: Exploration · Adventure · Singleplayer

Little Nightmares
Shared: Adventure · Singleplayer · Puzzle

The Room Two
Shared: Mystery · Puzzle · Adventure

MiSide
Shared: Story Rich · Singleplayer · 3D

Riven
Shared: Adventure · Exploration · Puzzle

Tomb Raider Game of the Year
Shared: Adventure · Story Rich · Singleplayer