Games like Age of Pixels
Games like Age of Pixels include Plague Inc: Evolved, Papers, Please, Mount & Blade II: Bannerlord, Game Dev Tycoon, and RimWorld. We matched them by the tags players give Age of Pixels on Steam (Indie, Strategy, Simulation, Retro, and Medieval): closest matches first, and among equally close ones the better-known games.

Plague Inc: Evolved
Shared: Strategy · Simulation · Indie

Papers, Please
Shared: Indie · Simulation · Retro

Mount & Blade II: Bannerlord
Shared: Strategy · Medieval · Simulation

Game Dev Tycoon
Shared: Indie · Simulation · Strategy

RimWorld
Shared: Strategy · Base Building · Simulation

Foundation
Shared: Simulation · Strategy · Medieval

Banished
Shared: Strategy · Simulation · Indie

Totally Accurate Battle Simulator
Shared: Simulation · Strategy · Indie

Crusader Kings II
Shared: Strategy · Simulation · Medieval

Parkitect
Shared: Simulation · Level Editor · Strategy

Crusader Kings III
Shared: Strategy · Simulation · Medieval

Dwarf Fortress
Shared: Simulation · Strategy · Base Building

Besiege
Shared: Simulation · Medieval · Indie

Kingdom Two Crowns
Shared: Strategy · Medieval · Base Building

Tavern Master
Shared: Simulation · Strategy · Indie

Ultimate Epic Battle Simulator
Shared: Simulation · Strategy · Medieval

Reus
Shared: Strategy · Indie · Simulation

FTL: Faster Than Light
Shared: Strategy · Indie · Replay Value

Creeper World 3: Arc Eternal
Shared: Strategy · Indie · Simulation

Door Kickers
Shared: Strategy · Simulation · Indie

Warsim: The Realm of Aslona
Shared: Simulation · Strategy · Indie

Naheulbeuk's Dungeon Master
Shared: Simulation · Replay Value · Strategy

Prison Architect
Shared: Simulation · Strategy · Base Building

Manor Lords
Shared: Strategy · Simulation · Base Building