Games like 49 Keys
Games like 49 Keys include Sally Face - Episode One, The Room Two, The Room Three, Strange Horticulture, and The Room. We matched them by the tags players give 49 Keys on Steam (Medieval, Magic, Dark, Mystery, and Demons): closest matches first, and among equally close ones the better-known games.

Sally Face - Episode One
Shared: Dark · Mystery · Psychological Horror

The Room Two
Shared: Mystery · Puzzle · Point & Click

The Room Three
Shared: Mystery · Puzzle · Point & Click

Strange Horticulture
Shared: Mystery · Dark · Puzzle

The Room
Shared: Mystery · Puzzle · Point & Click

Fran Bow
Shared: Point & Click · Dark · Puzzle

Cube Escape Collection
Shared: Mystery · Point & Click · Puzzle

Dagon: by H. P. Lovecraft
Shared: Dark · Lovecraftian · Atmospheric

The Room 4: Old Sins
Shared: Mystery · Puzzle · Point & Click

Rusty Lake Paradise
Shared: Point & Click · Puzzle · Mystery

Servant of the Lake
Shared: Puzzle · Point & Click · Mystery

The House of Da Vinci
Shared: Mystery · Puzzle · Point & Click

Poppy Playtime
Shared: Dark · Mystery · Puzzle

What Remains of Edith Finch
Shared: Mystery · Atmospheric · Dark

Strange Antiquities
Shared: Mystery · Dark · Puzzle

Endacopia
Shared: Point & Click · Dark · Puzzle

Tormentum - Dark Sorrow
Shared: Point & Click · Mystery · Dark

Detention
Shared: Dark · Puzzle · Psychological Horror

SOMA
Shared: Dark · Psychological Horror · Atmospheric

SIGNALIS
Shared: Dark · Psychological Horror · Mystery

Outer Wilds
Shared: Mystery · Puzzle · Adventure

The White Door
Shared: Mystery · Point & Click · Puzzle

A Plague Tale: Innocence
Shared: Medieval · Dark · Adventure

Little Nightmares II
Shared: Dark · Puzzle · Adventure